Call For Papers
Advancing enzyme science through rigorous research and open collaboration.
Submit Your Enzyme Research
The Journal of Enzymes is a distinguished Open Access and Peer-Reviewed publication dedicated to advancing enzymology and biochemistry. We publish rigorous studies that explain enzyme structure, function, regulation, and application across medicine, biotechnology, agriculture, and environmental systems.
Our readership includes researchers, clinicians, industrial scientists, and educators who rely on actionable enzyme science and reproducible methods.
We seek manuscripts that illuminate enzyme mechanisms, quantify catalytic performance, and translate enzymatic insights into real-world impact. Submissions should present clear hypotheses, robust experimental or computational methods, and practical relevance for enzymology or enzyme-enabled applications. Studies that compare enzyme variants, validate assays, or benchmark models against reference standards are welcome. Interdisciplinary work connecting chemistry, molecular biology, systems biology, and clinical translation is strongly encouraged.
Clinical/Medical Enzymology
We invite clinical studies that clarify enzyme biomarkers, diagnostic workflows, and enzyme-based interventions in human disease. Manuscripts may address enzyme deficiencies, enzyme replacement therapy, enzymatic drug metabolism, or the role of enzymes in inflammation, oncology, metabolic disorders, and rare genetic conditions.
Systems-Level Enzymology
We welcome research that maps enzyme networks, pathway dynamics, and multi-enzyme regulation at cellular or organismal scale. Topics include pathway rewiring, metabolic control analysis, enzyme co-factor balance, and systems biology approaches that link enzyme function to phenotype.
Therapeutic Enzyme Modalities
Submissions exploring therapeutic enzymes are encouraged, including enzyme replacement, enzyme prodrug activation, enzyme-based biologics, and enzyme mediated detoxification. We also welcome innovations in delivery systems, stability engineering, and clinical pharmacology.
Biocatalysis and Engineering
Research on enzyme engineering, directed evolution, rational design, biocatalysis, green chemistry, and industrial process optimization. Studies advancing sustainable biotechnology solutions through enzyme-based approaches are prioritized.
- Enzyme kinetics, catalytic efficiency, and reaction mechanisms
- Structural enzymology, protein folding, and conformational dynamics
- Enzyme engineering, directed evolution, and rational design
- Biocatalysis, green chemistry, and industrial process optimization
- Metabolic pathway analysis, flux modeling, and pathway control
- Enzyme inhibition, allosteric regulation, and drug discovery targets
- Enzyme assays, biosensors, and diagnostic enzymology
- Post-translational modifications and regulation of enzyme activity
- Computational enzymology, molecular modeling, and simulation
- Microbial, plant, and animal enzymology in health and disease
We publish original research, comprehensive reviews, short communications, methods papers, and translational reports. Authors are encouraged to present complete datasets, reproducible protocols, and clear conclusions that advance the enzymology field.
- Original Research Articles with full experimental or computational detail
- Systematic Reviews and Meta-Analyses where applicable
- Methods and Protocols that improve enzymatic measurement or modeling
- Short Communications reporting high-impact findings
- Case Reports or Clinical Notes tied to enzymatic diagnostics or therapy
Indexing: The articles appear in a wide range of abstracting and indexing databases, and are covered by numerous other services that aid discovery and access.
Article Processing Charges: JEN is a self-supporting journal and does not receive funding from any institution/government. Hence, the operation of the journal is supported by the processing fees received from authors.
Please ensure manuscripts include the following:
- Title page with author names, affiliations, and corresponding author details
- Structured abstract and 4 to 6 keywords aligned with enzymology focus
- Clear methods, enzyme assay conditions, and reproducible protocols
- Tables, figures, and supplementary materials with descriptive captions
- Appropriate statistical analysis and data availability statements
- Ethics approvals and compliance statements where applicable
- Clear limitations and uncertainty discussion
- References formatted consistently and accurately
Global Visibility
Open access distribution ensures your enzyme research reaches researchers, clinicians, and industry professionals worldwide without subscription barriers.
Fast Review Process
Expert editorial oversight with rapid review timelines. Average decision in 12 days from submission to help you publish your discoveries promptly.
Interdisciplinary Reach
Visibility across academia, industry, and clinical practice. Support for interdisciplinary studies connecting enzyme science to real-world applications.
Editorial Excellence
Clear editorial scope focused on enzymology and enzyme applications. Rigorous peer review ensuring high-quality publications in the field.
Authors should report reagent sources, enzyme purity, and assay conditions with enough detail to allow replication. For clinical or human data, include ethics approvals, consent statements, and data availability notes. For computational work, provide model parameters, code references, and validation benchmarks.
Submit Your Manuscript
Join the enzymology community advancing enzyme science and biocatalysis research.
OpenAccess is a great way to connect scientists and the public. It is not only beneficial to the public, but also to scientists who publish because the more people know and discuss scientific finds, the greater its impact becomes.
Do not hesitate to contact us if your research scope varies from the mentioned journal. We have ample journals dealing with various subjects. For your reference, here is the complete journals list.
Editorial inquiries should be directed to [email protected]
