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The Journal of Advanced Pharmaceutical Science and Technology (JAPST) publishes research on medicines: their discovery, properties, biological effects, formulation, manufacture, quality, safety and use in practice.
JAPSTISSN 2328-0182Pharmaceutical science, technology and practicePublished by Open Access Pub
JAPST covers pharmaceutical sciences and the technologies used to discover, evaluate, develop, produce and use medicines. Its remit includes drug discovery and medicinal chemistry, pharmacology and toxicology, pharmacognosy and natural products, pharmaceutics, pharmaceutical analysis, biotechnology, manufacturing and quality science. Clinical, translational and pharmacy-practice research belongs within this remit when the study addresses medicines or pharmaceutical care.
Pharmaceutical sciences encompass the study of drug substances, their actions and their use. Within this field, pharmaceutics addresses dosage forms and drug delivery; pharmacology examines drug action and response; and pharmaceutical technology applies methods and processes to pharmaceutical problems. These areas contribute different kinds of evidence.
A submission should make a clear contribution to pharmaceutical knowledge, technology, medicine safety or pharmacy practice. A new formulation or manufacturing process is not required for every study.
Drug discovery. A medicinal-chemistry study examines how changes in chemical structure affect biological activity, selectivity or drug-like properties.
Pharmaceutics. A dosage-form study evaluates release, stability, bioavailability or delivery performance.
Medicine safety. A pharmacovigilance study or documented adverse-drug-reaction case report contributes to understanding therapeutic risk.
Pharmacy practice. A clinical or community-pharmacy study evaluates medicine use, adherence, medication safety or pharmaceutical-care outcomes.
These domains describe the journal's central scientific coverage. Fundamental, applied and translational studies are considered according to their pharmaceutical question and the evidence appropriate to it.
Medicinal chemistry, drug and prodrug design, lead identification and optimization, structure–activity relationships, target validation and computational drug discovery. Chemical and molecular studies should establish their relevance to a drug, therapeutic target or pharmaceutical problem.
Drug mechanisms, pharmacodynamics, dose–response relationships, pharmacokinetics, absorption, distribution, metabolism and excretion, drug interactions, safety pharmacology and toxicology. Studies may address experimental systems or clinical drug response without requiring formulation innovation.
Phytochemistry, medicinal natural products, bioactive constituents, herbal medicines and ethnopharmacology with a defined pharmaceutical question. Work may examine identity, composition, biological activity, safety, standardization or quality, using authenticated materials and methods appropriate to the claims.
Preformulation, physical pharmacy, excipients, dosage forms, controlled and targeted delivery, nanomedicines and pharmaceutical biomaterials. Biopharmaceutics includes dissolution, permeability, bioavailability, bioequivalence and relationships between drug properties, dosage forms and biological performance.
Analytical method development and validation, drug and metabolite measurement, impurity and adulterant detection, stability-indicating assays, spectroscopy, chromatography, dissolution testing and process analytical technology. Methods should be evaluated for their intended pharmaceutical or bioanalytical use.
Process development, pharmaceutical engineering, scale-up, continuous manufacturing, stability, packaging, quality control and assurance, quality by design, validation and technology transfer. Regulatory science includes evidence and methods supporting pharmaceutical quality, safety, efficacy and regulatory evaluation.
Therapeutic proteins, peptides, antibodies, vaccines and nucleic-acid therapeutics; their discovery, biological evaluation, characterization, formulation, delivery or production. Biotechnology and bioinformatics fit when the pharmaceutical application is part of the research question.
JAPST also welcomes clinical pharmacology, pharmacotherapy, therapeutic drug monitoring, pharmacogenetics and pharmacogenomics, pharmacovigilance, pharmacoepidemiology and pharmacoeconomics. Clinical, hospital, community, social and public-health pharmacy studies may address prescribing, drug utilization, adherence, interactions, access to medicines, medication safety or pharmaceutical-care services. Their contribution can concern the use and effects of existing medicines; a new product or formulation is not a condition of scope.
A manuscript fits when its research question, evidence and contribution address pharmaceutical science, technology or practice.
Explain the pharmaceutical contribution directly and keep conclusions proportionate to the evidence. Merely mentioning a medicine does not establish scope fit.
Research from adjacent biomedical, chemical, computational, engineering, biological or public-health fields is welcome when it makes a meaningful contribution to a pharmaceutical question. The connection should be evident in the objectives, methods and interpretation.
New methods and applications are considered within the same scientific boundaries. Their inclusion depends on the pharmaceutical question and the strength of the evidence, rather than on the technology's novelty alone.
Subject fit and scientific quality are separate requirements. A topic may fit JAPST while a particular manuscript requires stronger methods, clearer reporting or better support for its conclusions.
JAPST welcomes original research, reviews, case reports and short communications within this scope, together with methodological and scholarly analysis formats. Study design and article format should be distinguished: clinical trials and observational studies are forms of research, while a systematic review is a form of evidence synthesis.
Report methods, material identity and provenance, controls, statistical analysis, uncertainty and limitations as applicable. Analytical studies need fit-for-purpose validation; natural-product studies need authenticated materials; clinical research needs appropriate ethics, consent and registration; and case reports need a clear clinical timeline and consent where required. Computational evidence and observational associations must be interpreted within their limits. Scope fit does not imply acceptance.
Journal of Advanced Pharmaceutical Science and Technology (JAPST)
ISSN 2328-0182 · Published by Open Access Pub · Pharmaceutical science, technology and practice